Main Article Content
Abstract
Asma merupakan penyakit heterogen yang disebabkan oleh inflamasi kronis saluran pernafasan. Pada tahun 2019, prevalensi asma di Indonesia berjumlah 4,5%. Provinsi Lampung tercatat memiliki prevalensi asma sejumlah 1,6% di tahun 2018. Kasus seorang wanita, usia 42 tahun, mengeluhkan sesak nafas 30 menit Sebelum Masuk Rumah Sakit (SMRS). Sesak nafas terakhir muncul 2 bulan yang lalu dan sesak nafas saat malam hari muncul 2 bulan yang lalu. Sesak nafas muncul ketika dipicu oleh debu, asap, dan cuaca dingin. Sesak nafas memberat ketika malam dan pagi hari. Keluhan penyerta berupa batuk tidak berdahak dan riwayat alergi terhadap debu, asap, dan cuaca dingin. Pemeriksaan fisik didapatkan pasien bernafas cepat, wheezing, dan obesitas grade II. Pada pemeriksaan penunjang, pasien mengalami anemia, eusinophilia, dan indikasi penyakit paru kronis pada gambaran rontgen thorax. Diagnosis pasien berupa asma eksaserbasi sedang persisten berat tidak terkontrol dengan obesitas dan anemia. Pasien diberikan tatalaksana farmakologi berupa nebulisasi Short Acting Beta Agonist (SABA) dan nebulisasi kortikosteroid. Setelah 3 hari rawat inap, pasien mengalami perbaikan klinis dan diperbolehkan pulang
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Copyright (c) 2024 Syazili Mustofa, Muhammad Alif Ramadhan, Giska Tri Putri, Novita Carolia, Cahyo Wisnugroho

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References
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References
Brihi, J.E. dan Pathak S. (2024). Normal and Abnormal Complete Blood Count With Differential [Internet]. Treasure Island (FL): StatPearls Publishing. Diakases dari: https://www.ncbi.nlm.nih.gov/books/NBK604207/
Geng, W., Batu, W., You, S., Tong, Z., He, H. (2020). High-Flow Nasal Cannula: A Promising Oxygen Therapy for Patients with Severe Bronchial Asthma Complicated with Respiratory Failure, Canadian Respiratory Journal, Doi: 10.1155/2020/2301712.
GINA. (2024). Global Strategy For Asthma Management and Prevention.
Gondal, A.Z. dan Zulfiqar, H. (2023). Amynophilline. Dalam: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. Diakases dari: https://www.ncbi.nlm.nih.gov/books/NBK545175/
Gottwalt, B. dan Tadi, P. (2023). Methylxanthine. Dalam: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. Diakases dari: https://www.ncbi.nlm.nih.gov/books/NBK559165/
Habib, N., Pasha, M., Tang, D. (2022). Current Understanding of Asthma Pathogenesis and Biomarkers, Cells, 11(17): 1-17.
Hafen, B., Sharma, S. (2022). Oxygen Saturation [Internet]. Treasure Island (FL): StatPearls Publishing. Diakases dari: https://www.ncbi.nlm.nih.gov/books/NBK525974/
Hasmi, M., Cataletto, M. (2024). Asthma [Internet]. Treasure Island (FL): StatPearls Publishing. Diakases dari: https://www.ncbi.nlm.nih.gov/books/NBK430901/
Inokuchi, R., Aoki, A., Aoki, Y., Yahagi, N. (2014). Effectiveness of Inhaled Furosemide for Acute
Asthma Exacerbation: A Meta-Analysis, Critical Care, 621(18), 1-6.
Kemenkes RI. (2016). Program Penatalaksanaan Asma. https://p2ptm.kemkes.go.id/dokumen-ptm/program-penatalaksanaan-asma
Kemenkes RI. (2018). Laporan Riskesdas Provinsi Lampung 2018. Jakarta: Lembaga Penerbit Badan Litbang Kesehatan.
Kemenkes RI. (2020). Asma. https://yankes.kemkes.go.id/view_artikel/1433/asma
Mizuta, K., Matoba, A., Shibata, S., Masaki, E., Sr, C.W. (2019). Obesity-Induced Asthma: Role of Free Fatty Acid Receptors, Japanese Dental Science Review, Volume 55, 103-107.
Mohanan, S., Tapp, H., McWilliams, A., Dulin, M. (2014). Obesity and Asthma: Pathophysiology and implications for Diagnosis and Management in Primary Care. Experimental Biology and Medicine. 239(11): 1531-1540.
Mustofa S, Infoanto A, Soemarwoto R, Saputra T, Rosari F, Dorisman H. (2023). Aktualisasi Manajemen Tatalaksana Penyakit Paru Obstruktif Kronik (PPOK) dan Asma Pada Fasilitas Kesehatan Tingkat Pertama (FKTP) di Kota Metro. Jurnal Pengabdian Masyarakat Ruwa Jurai. 8(2): 66-70.
Mustofa, S. (2023). Occupational Asthma, Jurnal Kedokteran Unila, 7(2), 84-88.
Naqvi, A., Patel, P., dan Gerriets, V. (2024). Cetirizine [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK549776/
Rhew, K., Choi, J., Kim, K., Choi, K.H., Lee, S., Park, H. (2023). Increased Risk of Anemia in Patients with Asthma, Clinical Epidemiology, Volume 15, 31-38.
Soemarwoto, R., Mustofa, S., Rusmini, H., Febriani, A., Muslimah, N. (2020). Relationship Between Allergic Rhinitis and Asthma in The Elementary School Children in Bandar Lampung, Indonesia, European Respiratory Journal, 56(64), 670.
Susanto, A., Purwitasari, M., Antariksa, B., Soemarwoto, R., Mustofa, S. (2018). Dampak Polusi Udara terhadap Asma, Jurnal Kedokteran Unila, 2(2), 163-173.
Training, T. (2012). Chronic Obstructive Pulmonary Disease, Case Study, Doi: https://doi.org/10.53347/rID-19446. Diakses melalui: https://radiopaedia.org/cases/19446
Vora, A. dan Nadkar, M. (2015). Codein: A Relook at The Old Antitussive, The Journal of The Association of Physicians of India, 63(4), 80-85.
Weerakkody, Y. et al. (2013). Asthma. Doi: https://doi.org/10.53347/rID-23925. Diakses melalui: https://radiopaedia.org/articles/23925
WHO. (2024). Asthma. https://www.who.int/news-room/fact-sheets/detail/asthma
Weiss, G., Ganz, T., Goodnough, L. (2019). Anemia of Inflammation, Blood Journal, 133(1): 40-50.