Main Article Content
Abstract
Ekstrak buah Clidemia hirta telah dipilih sebagai mitra reaksi dengan senyawa kloroaurat dalam reaksi yang menghasilkan nanopartikel emas. Ekstrak buah Clidemia hirta diperoleh dengan cara sederhana yaitu dengan memanaskan buah dalam air demineralisasi pada suhu 70 ºC. Ekstrak yang diperoleh dicampur dengan larutan yang mengandung ion emas pada suhu kamar. Reaksi berlangsung cepat, ditunjukkan dengan perubahan warna ekstrak yang cepat ketika ditambahkan tetes demi tetes ke dalam larutan ion emas. Berdasarkan analisis Transmission Electron Microscope (TEM) ukuran partikel berada di antara ukuran nano dan mikro. Hasil analisis menggunakan particle size analyzer (PSA) menunjukkan bahwa kondisi saat ini memberikan rata-rata ukuran partikel sebesar 121 nm.
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Copyright (c) 2025 Octakireina Liesaiani Daefisal, Demi Dama Yanti, I Putu Mahendra, Muhamad Alvin Reagen, Etriyanto Arman, Salprima Yudha S

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References
Hu, X.; Zhang, Y.; Ding, T.; Liu, J.; Zhao, H. Multifunctional Gold Nanoparticles: A Novel
Nanomaterial for Various Medical Applications and Biological Activities. Front Bioeng
Biotechnology 2020,8(August),1–17. DOI : 10.3389/fbioe.2020.00990.
Mikhailova, E.O. Gold nanoparticles: Biosynthesis and potential of biomedical application. Journal of Functional Biomaterial 2021,12(4), 1-31. DOI:
3390/jfb12040070
Basavegowda, N.; Kumar, G.D.;, Tyliszczak, B.; Wzorek, Z.; Sobczak-Kupiec, A. One- step synthesis of highly-biocompatible spherical gold nanoparticles using Artocarpus heterophyllus Lam. (jackfruit) fruit extract and its effect on pathogens. Annals of Agricultural and Environmental Medicine 2015,22(1),84–9. DOI:
5604/12321966.1141374
Lee, K.X.; Shameli, K.; Miyake, M.; Kuwano, N.; Bt Ahmad K.N.B.; Bt Mohamad S.E.; Yew, Y.P. Green Synthesis of Gold Nanoparticles Using Aqueous Extract of Garcinia mangostana Fruit Peels. Journal of Nanomaterial 2016, 1-7. DOI :
1155/2016/8489094
Basavegowda, N.; Sobczak-Kupiec, A.; Malina, D.; Yathirajan, H.S.; Keerthi, V.R.; Chandrashekar, N.; Dinkar, S.; Liny, P. Plant mediated synthesis of gold nanoparticles using fruit extracts of ananas comosus (L.) (pineapple) and evaluation of biological activities. Advanced Materia Letter 2013,4(5),332–7. DOI: 10.5185/amlett.2012.9423
Bogireddy, N.K.R.; Martinez G.L.; Osorio-Roman, I.; Agarwal, V. Synthesis of gold nanoparticles using Coffea Arabica fruit extract. Advanced in Nano Research
,5(3),253–260. DOI: 10.12989/anr.2017.5.3.253.
Mahmood, H.;Hussain, S.B.; Nosheen, A.; Mahmood, T.; Shafique, M.; Ul-Haq, N.; Ul Haq, A. Antibacterial Activities of Gold Nanoparticles Synthesized By Citrus Limonum Fruit Extract. Pakistan Journal of Botany 2021,53(6),2305–2310. DOI:
30848/PJB2021-6(36)
Lestari, G.A.D.; Cahyadi, K.D. Biosynthesis of Gold Nanoparticles Mediated by
Andaliman Fruit Water Extract and Its Application as Antioxidants. Jurnal Kimia
Sains dan Aplikasi 2022,25(2),56–62. DOI: 10.14710/jksa.25.2.56-62.
Dewi, R.K.; Firdaus, M.L. Biosintesis Nanopartikel Emas Menggunakan Belimbing
Wuluh ( Averrhoa bilimbi ) untuk Analisis Kromium. Jurnal Kependidikan Kimia
,12(February),44–55. DOI : 10.33394/hjkk.v12i1.10188.
Fadhli, H.; Ikhtiarudin, I.; Lestari, P. Isolasi dan Uji Aktivitas Antioksidan Ekstrak Metanol Dari Buah Senduduk Bulu (Clidemia hirta (L.) D. Don). Pharmacon Jurnal Farmasi Indonesia 2020,17(2), 92–100. DOI: 10.23917/pharmacon.v17i2.9846.
Rani, M. Uji Efektivitas Green Synthesis Nanopartikel Perak (AgNPs) Menggunakan Ekstrak Daun Clidemia hirta untuk Mengendalikan Ganoderma boninense Secara In Vitro. Undergraduate Thesis 2023, Universitas Sumatera Utara.
Syafiuddin, A.; Salmiati.; Hadibarata, T.; Beng, H.K.A.; Razman, S.M. Novel weed - extracted silver nanoparticles and their antibacterial appraisal against a rare bacterium from river and sewage treatment plan. Nanomaterials 2018,8(1),1-17. DOI: 10.3390/nano8010009.
Philip, D. Green Synthesis of Gold and Silver Nanoparticles using Hibiscus rosasinensis, Physica E. 2010. 42(5): 1417- 1424.
Akilandaeaswari, B., Muthu, K. Green Method for Synthesis and Characterization of Gold Nanoparticles Using Lawsonia inermis Seed Extract and Their Photocatalytic Activity. Materials Letters 2020, 277, 128344. doi: https://doi.org/10.1016/j.matlet.2020.1
Matutu, J.M.; Maming.; Taba, P., Sintesis Nanopartikel Perak dengan Metode Reduksi Menggunakan Buah Merah (Pandanus Conoideus) Sebagai Bioreduktor. Jurusan Kimia FMIPA UNHAS. 2016.
Amiruddin, M. A.; Taufikurrohmah, T. Material Peredam Radikal Synthesis and Characterization of Gold Nanoparticle Using a Matrix of Bentonite in Scavenging Free Radicals in Cosmetics. UNESA Journal of Chemistry Vol. 2, No. 1, January 2013,
(1), 68–75.
Kumar, B.; Cumbal, L., UV-Vis, FTIR and antioxidant study of Persea Americana (Avocado) leaf and fruit: A comparison UV-Vis, FTIR yestudio antioxidante de Persea Americana hoja y fruto (Avocado): Una comparaci. Revista de la Facultad de Ciencias Quimicas 2016, 15, 13–20.