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Abstract
[PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF SOME FRACTIONS FROM BARK OF CASTOR (Ricinus communis L.)]. The Phytochemical screening was conducted to determine secondary metabolites found in the bark of castor (Ricinus communis L.).The test results of phytochemical screening that has been done presence of phenolic, flavonoids, alkaloids, saponins, and terpenoids. Extraction is done by maceration using ethanol 96%. Tests performed on the fraction of the antioxidant activity of ethanol, ethyl acetate, n-hexane, and ascorbic acid as compared to using DPPH. The results of measuring the antioxidant activity using Uv-Vis Spectrophotometer IC50 values obtained succession namely fraction of ethanol, ethyl acetate, n-hexane, and ascorbic acid, 33,38, 24,38, 289, 05 and 12, 48 ppm. Fraction of ethanol and ethyl acetate has a very strong antioxidant activity due IC50<50 ppm while the n-hexane fraction very weak antioxidant activity. Phenolic and flavonoids the bark of castor that can be potentially as antioxidants
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References
- Andriani Y. Pengaruh Ekstrak Daun Jati Belanda (Guazuma ulmifolia Lamk.) Terhadap Bobot Badan Kelinci yang Diberi Pakan Berlemak. Jurnal Gradien. 2005 : 1(2): 74-76.
- Droge,W. Free Radicals in The Physiological Control of Cell Function, Pysiol Rev. 2002: 82: 47-95.
- Dungir, S.G., Dewa. G. Katja, Vanda .S. Kamu, Aktivitas Antioksidan Ekstrak Fenolik dari Kulit Buah Manggis (Garcinia mangostana L). Jurnal MIPA UNSRAT Online. 2012: 1(1): 11-15.
- Andriani Y. Uji Aktivitas Antioksidan Ekstrak Betaglukan Dari Saccharomyces cerevisiae. Jurnal Gradien. 2007 : 3(1): 226-230.
- Miller .,H.E.,F Rigelholf, L Marquart, A Prakash, M Kanter. Antioxidant content of whole grain breakfast cereals, fruits and vegetables. Journal of The American College of Nutrition. 2000: 19(3): 312S-319S.
- Windono, T, Soediman, S., Yudawati,U., Ermawati, E., Srielita, Erowati, T.I. Uji Peredam Radikal Bebas Terhadap 1,1-Diphenyl-2-Picrylhydrazyl (DPPH) dari Ekstrak Kulit Buah dan Biji Anggur (Vitis vinifera L) Probolinggo Biru dan Bali. Artocarpus, 2001 :1 :34-43.
- Astuti,S., Isoflavon Kedelai dan Potensinya Sebagai Penangkap Radikal Bebas. Jurnal Teknologi Industri dan Hasil Pertanian. 2008:13(2): 126-136.
- Adawiah, Dede Sukandar, Anna Muawanah. Aktivitas Antioksidan Dan Kandungan Komponen Bioaktif Sari Buah Namnam, Jurnal Kimia VALENSI : Jurnal Penelitian dan Pengembangan Ilmu Kimia, 2015: 1(2): 130-136.
- Niah, R., Helda. Aktivitas Antioksidan Ekstrak Etanol Kulit Buah Naga Merah Daerah Pelaihari, Kalimantan Selatan dengan Metode DPPH (2,2-difenil-1-pikrilhidrazil). Jurnal Pharmascience. 2016: 3(2): 36-42.
- A.Mohamad,H., Rosmiati., Muhammad, T.S.T., Andriani,Y., Bakar, K., Ismail,N., Saidin,J., Latip, J., Musa, N., Perenrengi. Potential Secondary Metabolites from Ma-rine Sponge Aaptos aaptos for Artheros-clerosis and Vibriosis Treatments, NPC (Natural Product Communications).2017 : 12(8): 1227-1230.
- Andriani Y. Toksisitas Fraksi Aktif Steroid Ekstrak Daun Jati Belanda (Guazuma Ulmifolia Lamk.) Terhadap Aktivitas Serum Glutamat Oksalat Transaminase (SGOT) Dan Serum Glutamat Piruvat Transaminase (SGPT) Pada Tikus Putih. Jurnal Gradien. 2008 : 4 (2): 365-371.
- Pangestu,N,S, Nurhamidah, Elvinawati. Aktivitas Antioksidan dan Anti Bakteri Ekstrak Daun Jatropha gossypifolia L. Alotrop. 2017: 1 (1): 15-19.
- Sarfina, J, Nurhamidah, Dewi Handayani. 2017. Uji Aktivitas Antioksidan dan Anti-bakteri Ekstrak Daun Ricinus communis L (Jarak Kepyar). Alotrop. 2017: 1(1): 66-70.
- Marliana,S.D.,Venty,S.,Suryono. Skrining Fitokimia dan Analisis KLT Komponen Kimia Buah Labu Siam (Sechum edule Jacq Swurtz) dalam Ekstrak Etanol. Biofarmasi. 2005 : 3(1): 26-34.
- Ningsih. D.R., Zusfahair, Dwi Kartika. Indentifikasi Senyawa Metabolit Sekunder Serta Uji Aktivitas Ekstrak Daun Sirsak Sebagai Antibakteri, Molekul. 2016: 11(1): 101-111.
- Minhatun N., Tukiran, Suyatno, dan Nurul Hidayati. Uji Skrining Fitokimia Pada Ekstrak Heksan, Kloroform dan Metanol dari Tanaman Patikan Kebo (Euphorbiaehirtae). Prosiding Seminar Nasional Kimia,ISBN:978-602-0951-00-3, Jurusan Kimia FMIPA Universitas Negeri Surabaya, 20 September 2014 : B-279 - B-286.
- Mohamad. H, Andriani.Y, Kamariah.B., Siang. C.C., Syamsumir, D.F., Alias, A., Radzi, S.A.M., Effect of drying method on anti-microbial , anti-oxidant activities and isolation of bioactive coumpounds from Peperomia pellucida (L) Hbk, Journal of Chemical and Pharmaceutical Research, 2015 : 7(9): 578-584.
- Puspitasari, M.L.,Tara Viantya Wulansari, Tri Dewanti Widyaningsih, Jaya Mahar Maligan, Nurida Panca Nugrahini, Aktivitas Antioksidan Suplemen Herbal Daun Sirsak (Annona muricata L ) dan Kulit Manggis (Garcinia mangostana L): Kajian Pustaka, Jurnal Pangan dan Agroindustri. 2016: 4(1): 283-290.
- Molyneux, P. The Use of the Stable Free Radical diphenylpicrylhydrazyl (DPPH) for Estimating Antioxidant Activity. J. Sci. Technol, 2004: 26 (2): 211-219.
- Andriani Y, Wahid MEA Muhammad TST and Mohamad H. AntibacterialL, Radical – Scavenging Activities And Cytotoxicity Properties Of Phaleria macrocarpa (Scheff.) Boerl leaves In HEPG2 Cell Lines International Journal of Pharmaceutical Science and Research. 2011 : 2 (7 ): 1700-1706.
- Utami, W.W., Aktsar Roskiana Ahmad., Abd. Malik. Uji Aktivitas Larvasida Eks-trak Daun Jarak Kepyar (Ricinus communis L) Terhadap Larva Nyamuk Aedesaegypti. Jurnal Fitofarmaka Indonesia. 2016: 3(1): 141-145.
- H.O.Odeoga, D.E. Okwu, and B.O.Mbaebie. Phytochemical constituents of some Nigerian medicinal plants, African Journal of Biotechnology. 2005: 4(7): 685-688.
References
Andriani Y. Pengaruh Ekstrak Daun Jati Belanda (Guazuma ulmifolia Lamk.) Terhadap Bobot Badan Kelinci yang Diberi Pakan Berlemak. Jurnal Gradien. 2005 : 1(2): 74-76.
Droge,W. Free Radicals in The Physiological Control of Cell Function, Pysiol Rev. 2002: 82: 47-95.
Dungir, S.G., Dewa. G. Katja, Vanda .S. Kamu, Aktivitas Antioksidan Ekstrak Fenolik dari Kulit Buah Manggis (Garcinia mangostana L). Jurnal MIPA UNSRAT Online. 2012: 1(1): 11-15.
Andriani Y. Uji Aktivitas Antioksidan Ekstrak Betaglukan Dari Saccharomyces cerevisiae. Jurnal Gradien. 2007 : 3(1): 226-230.
Miller .,H.E.,F Rigelholf, L Marquart, A Prakash, M Kanter. Antioxidant content of whole grain breakfast cereals, fruits and vegetables. Journal of The American College of Nutrition. 2000: 19(3): 312S-319S.
Windono, T, Soediman, S., Yudawati,U., Ermawati, E., Srielita, Erowati, T.I. Uji Peredam Radikal Bebas Terhadap 1,1-Diphenyl-2-Picrylhydrazyl (DPPH) dari Ekstrak Kulit Buah dan Biji Anggur (Vitis vinifera L) Probolinggo Biru dan Bali. Artocarpus, 2001 :1 :34-43.
Astuti,S., Isoflavon Kedelai dan Potensinya Sebagai Penangkap Radikal Bebas. Jurnal Teknologi Industri dan Hasil Pertanian. 2008:13(2): 126-136.
Adawiah, Dede Sukandar, Anna Muawanah. Aktivitas Antioksidan Dan Kandungan Komponen Bioaktif Sari Buah Namnam, Jurnal Kimia VALENSI : Jurnal Penelitian dan Pengembangan Ilmu Kimia, 2015: 1(2): 130-136.
Niah, R., Helda. Aktivitas Antioksidan Ekstrak Etanol Kulit Buah Naga Merah Daerah Pelaihari, Kalimantan Selatan dengan Metode DPPH (2,2-difenil-1-pikrilhidrazil). Jurnal Pharmascience. 2016: 3(2): 36-42.
A.Mohamad,H., Rosmiati., Muhammad, T.S.T., Andriani,Y., Bakar, K., Ismail,N., Saidin,J., Latip, J., Musa, N., Perenrengi. Potential Secondary Metabolites from Ma-rine Sponge Aaptos aaptos for Artheros-clerosis and Vibriosis Treatments, NPC (Natural Product Communications).2017 : 12(8): 1227-1230.
Andriani Y. Toksisitas Fraksi Aktif Steroid Ekstrak Daun Jati Belanda (Guazuma Ulmifolia Lamk.) Terhadap Aktivitas Serum Glutamat Oksalat Transaminase (SGOT) Dan Serum Glutamat Piruvat Transaminase (SGPT) Pada Tikus Putih. Jurnal Gradien. 2008 : 4 (2): 365-371.
Pangestu,N,S, Nurhamidah, Elvinawati. Aktivitas Antioksidan dan Anti Bakteri Ekstrak Daun Jatropha gossypifolia L. Alotrop. 2017: 1 (1): 15-19.
Sarfina, J, Nurhamidah, Dewi Handayani. 2017. Uji Aktivitas Antioksidan dan Anti-bakteri Ekstrak Daun Ricinus communis L (Jarak Kepyar). Alotrop. 2017: 1(1): 66-70.
Marliana,S.D.,Venty,S.,Suryono. Skrining Fitokimia dan Analisis KLT Komponen Kimia Buah Labu Siam (Sechum edule Jacq Swurtz) dalam Ekstrak Etanol. Biofarmasi. 2005 : 3(1): 26-34.
Ningsih. D.R., Zusfahair, Dwi Kartika. Indentifikasi Senyawa Metabolit Sekunder Serta Uji Aktivitas Ekstrak Daun Sirsak Sebagai Antibakteri, Molekul. 2016: 11(1): 101-111.
Minhatun N., Tukiran, Suyatno, dan Nurul Hidayati. Uji Skrining Fitokimia Pada Ekstrak Heksan, Kloroform dan Metanol dari Tanaman Patikan Kebo (Euphorbiaehirtae). Prosiding Seminar Nasional Kimia,ISBN:978-602-0951-00-3, Jurusan Kimia FMIPA Universitas Negeri Surabaya, 20 September 2014 : B-279 - B-286.
Mohamad. H, Andriani.Y, Kamariah.B., Siang. C.C., Syamsumir, D.F., Alias, A., Radzi, S.A.M., Effect of drying method on anti-microbial , anti-oxidant activities and isolation of bioactive coumpounds from Peperomia pellucida (L) Hbk, Journal of Chemical and Pharmaceutical Research, 2015 : 7(9): 578-584.
Puspitasari, M.L.,Tara Viantya Wulansari, Tri Dewanti Widyaningsih, Jaya Mahar Maligan, Nurida Panca Nugrahini, Aktivitas Antioksidan Suplemen Herbal Daun Sirsak (Annona muricata L ) dan Kulit Manggis (Garcinia mangostana L): Kajian Pustaka, Jurnal Pangan dan Agroindustri. 2016: 4(1): 283-290.
Molyneux, P. The Use of the Stable Free Radical diphenylpicrylhydrazyl (DPPH) for Estimating Antioxidant Activity. J. Sci. Technol, 2004: 26 (2): 211-219.
Andriani Y, Wahid MEA Muhammad TST and Mohamad H. AntibacterialL, Radical – Scavenging Activities And Cytotoxicity Properties Of Phaleria macrocarpa (Scheff.) Boerl leaves In HEPG2 Cell Lines International Journal of Pharmaceutical Science and Research. 2011 : 2 (7 ): 1700-1706.
Utami, W.W., Aktsar Roskiana Ahmad., Abd. Malik. Uji Aktivitas Larvasida Eks-trak Daun Jarak Kepyar (Ricinus communis L) Terhadap Larva Nyamuk Aedesaegypti. Jurnal Fitofarmaka Indonesia. 2016: 3(1): 141-145.
H.O.Odeoga, D.E. Okwu, and B.O.Mbaebie. Phytochemical constituents of some Nigerian medicinal plants, African Journal of Biotechnology. 2005: 4(7): 685-688.