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Submitted
November 1, 2019
Accepted
November 25, 2019
Published
November 2, 2020
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Abstract
ABSTRAK
Meningioma merupakan tumor yang paling umum terjadi pada sistem saraf pusat (SSP), berasal dari sel meningothelial lapisan arakhnoid. Programmed Death Ligand 1 (PD-L1) merupakan protein immune checkpoint yang akan menyebabkan imun antitumor tersupresi. Pada meningioma high grade, sel T regulator dan ekspresi PD-L1 meningkat yang disebabkan karena immunosuppressive tumor microenvironment sehingga tumor menjadi agresif. Tingkat ekspresi PD-L1 tidak ditetapkan dalam meningioma. Tergantung pada tingkat ekspresi, anti-PD-L1, mungkin merupakan pengobatan yang efektif untuk meningioma.
Kata Kunci : meningioma, PD-L1, Anti PD-L1
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How to Cite
janah, raudatul. (2020). EKSPRESI PD-L1 PADA MENINGIOMA. Jurnal Kedokteran Raflesia, 6(1), 1–10. https://doi.org/10.33369/juke.v6i1.9350