Main Article Content
Abstract
Heat stress causes a decrease in metabolic function and immunity, which results in a decrease in production. The provision of natural extracts such as the active compound dyally n-suldifa (Dn-S) is one strategy to overcome the adverse effects of heat stress. One hundred and twenty-five female laying native chickens, with an average body weight of 1213.83±15.52 g, 40 weeks old, were used in this experiment, to study the impact of Dn-S administration from garlic on the metabolite profile of the glycogenolysis pathway. laying. Laying hens were distributed into five treatment groups, each with 25 samples. Dn-S isolation from garlic isolated by distillation technique. The study was carried out with five types of experimental treatments, as follows the group with a comfort zone temperature (24°C) and without the administration of Diallyl n-Sulfide (Dn-S), heat stress (38°C) and without Dn-S, heat stress (38°C) and 100 µL Dn-S, heat stress (38°C) and 125 µL Dn-S, heat stress (38°C) and 150 µL Dn-S/head. Based on the results of the study, it was shown that heat stress causes an increase in the rate of glycogenolysis and intermediate metabolites and their catalyzing enzymes. It appears that the administration of 150 µL Dn-S, effectively reduces the rate of glycogenolysis. It was concluded that heat stress on laying hens could be avoid by administering garlic Dn-S.
Keywords
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References
Adriani, L, Abun and A. Mushawwir. 2015. Effect of dietary supplementation of Jengkol (Pithecellobium jiringa) skin extract on blood biochemistry and gut flora of broiler chicken. International Journal of Poultry Science 14: 407-410. DOI: 10.3923/ijps.2015.407.410
Adriani, L. and A. Mushawwir. 2020. Correlation Between Blood Parameters, Physiological and Liver Gene Expression Levels in Native Laying Hens Under Heat Stress. IOP Conf. Series: Earth and Environmental Science 466: 1-7. DOI:10.1088/1755-1315/788/1/012091
Adriani, L., A. Mushawwir, B.R. Anastasia and B. Rahayu. 2018. Effect of combination chitosan and turmeric powder (curcuma domestica val.) For improving blood lipid profile in broilers. Scientific Papers. Series D. Animal Science. LXI (1):225-229. DOI: 10.3244/j.ass./2018.99.021
Allen, J.D., L. W. Hall, R.J. Collier and J.F. Smith. 2015. Effect of core body temperature, time of day, and climate conditions on behavioral patterns of lactating dairy cows experiencing mild to moderate heat stress. Journal Dairy Science 98: 118-27. DOI: 10.3168/jds.2013-7704
Ammer, S, C. Lambertz, D. von Soosten, K. Zimmer, U. Meyer, S. Dänicke and M. Gauly. 2018. Impact of diet composition and temperature-humidity index on water and dry matter intake of high-yielding dairy cows. J. Anim. Physiol. Anim. Nutr. (Berl.). 102: 103-113. DOI: 10.1111/jpn.12664
Burdick, N. C, J.A. Carroll, R. Randel, S. Willard, R. Vann, C.C. Chase, S. Lawhon, L.E. Hulbert and J.T. Welsh. 2011. Influence of Temperament and Transportation on Physiological and Endocrinological Parameters in Bulls. Livestock Science. 139: 213-221. DOI: 10.1017/S1466 252318000075
Cai, X., Y.H. Chiu, and Chen ZJ. 2014. The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling. Molecular Cell 54: 289-296. DOI: 10.1016/j.molcel.2014.03.040
Carrol, E.C., L. Jin, A. Mori, M.N. Wolf, E. Oleszycka, H.B.T. Moran, S. Mansouri, C.P. McEntee, E. Lambe, E.M.
Agger, P. Andersen, C. Cunningham, P. Hertzog, K.A. Fitzgerald, A.G. Bowie and E.C. Lavelle. 2016. The Vaccine Adjuvant Chitosan Promotes Celluler Immunity Via DNA Sensor Cgas-STING-Dependent Induction of Type I Interferons. Immunity 44: 1-12. DOI: 10.1016/j.immuni.2016.02.004
Dinana, A., D. Latipudin, D. Darwis dan A. Mushawwir. 2019. Profil Enzim Transaminase Ayam Ras Petelur Yang Diberi Kitosan Iradiasi. Jurnal Nutrisi Ternak Tropis dan Ilmu Pakan 1 (1):6-15. DOI: http://dx.doi.org/10.24198/jnttip.v1i1.25425
Fabris, T.F., J. Laporta and F.N. Corra. 2017. Effect of nutritional immunomodulation and heat stress during the dry period on subsequent performance of cows. Journal Dairy Science 100: 6733-6742. DOI: https://DOI.org/10.3168/jds.2016-12313
Gehrke, N., C. Mertens, T. Zillinger, J. Wenzel, T. Bald, S. Zahn, T. Tuting, G.W. Hartmann and W. Barchet. 2013. Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Pontentiates STING-Dependent Immune Sensing. Immunity 39:482-495. DOI: https://DOI.org/10.1016/j.immuni.2013.08.004
Gray, L.R., M.R. Sultana and A. J.Rauckhorst. 2015. Hepatic mitochondrial pyruvate carrier 1 is required for efficient regulation of gluconeogenesis and whole-body glucose homeostatis. Cell Metabolism. 22: 669-681. DOI: https://DOI.org/10.1016/ j.cmet.2015.07.027
Hernawan, E, L. Adriani and A. Mushawwir, C. Cahyani and D. Darwis. 2017. Effect of dietary supplementation of chitosan on blood biochemical profile of laying hens. Pakistan Journal Nutrition 16: 696-699. DOI: https://dx.DOI.org/10.3923/pjn.2017.696.699
Ippolito, D. L., J. A. Lewis, C. Yu, L.R. Leon and J.D. Stallings. 2014. Alteration in circulating metabolites during and after heat stress in the conscious rat: potential biomarkers of exposure and organ specific injury. BMC Physiology 14: 23-29.DOI: https://dx.DOI.org/ 10.1186%2Fs12899-014-0014-0
István, F., L. Zsolt and O. László. 2020. Relationship of dairy heifer reproduction
with survival to first calving, milk yield and culling risk in the first lactation. Asian-Australasian Journal of Animal Sciences. 33: 1360-1368. DOI: 10.5713/ajas.19.0474
Jiwandini, A., Burhanudin dan A. Mushawwir. 2020. Kadar enzim transaminase (sgpt, sgot) dan gamma glutamyl transpeptidase (? -gt) pada ayam petelur fase layer yang diberi ekstrak pegagan (Centella asiatica). Jurnal Nutrisi Ternak Tropis dan Ilmu Pakan. 2(2):112-119. DOI: https://doi.org/10.24198/jnttip.v2i2.27389
Kamil, K.A., D. Latipudin, A. Mushawwir, D. Rahmat and R. L. Balia. 2020. The Effects of ginger volatile oil (GVO) on the metabolic profile of glycolytic pathway, free radical and antioxidant activities of heat-stressed cihateup duck. International Journal on Advanced Science, Engineering and Information Technology 10:1228-1233. DOI: 10.1817/ijaseit.10.3.11117
Khan, S., K. Anwar, K. Kaleem, A. Saeed, H. Nabi, A. Hayat, Z. Ahmad, F. Hayan and Safirullah. 2015. Study of phenotypic and morphometric characteristics of Achai cattle at Livestock Research and Development Station Dir (Lower), Pakistan. Pakistan Journal Nutrition 14: 201-203. DOI: 10.4737/pjn.2015.452.774
Loyau, T, S. Metayer-Coustard , C. Berri, S. Crochet, S. Cailleau-Audouin, M. Sannier, P. Chartrin, C. Praud, C.
Hennequet-Antier, N. Rideau, N. Courousse, N. Mignon-Grasteau, N. Everaert, M. J. Duclos, S. Yahav, S. Tesseraud and A. Collin. 2014. Thermal manipulation during embryogenesis has longterm effects on muscle and liver metabolism in fast-growing chickens. PLoS One 9: e105339. http://dx.DOI.org/ plosone/10.1016/P.2014.08.444
Mushawwir, A., L. Adriani and K.A. Kamil. 2011. Prediction models for olfactory metabolic and sows % RNAreticulocyt (RNArt) by measurement of atmospheric ammonia exposure and microclimate level. Journal of The Indonesian Tropical Animal Agriculture. 36: 14-20. DOI: https://DOI.org/10.14710/jitaa.36.1.14-20
Mushawwir, A., U.H. Tanuwiria, K.A. Kamil, L. Adriani, R. Wiradimadja and N. Suwarno. 2018. Evaluation of haematological responses and blood biochemical parameters of heat-stressed broilers with dietary supplementation of javanese ginger powder (Curcuma xanthorrhiza) and garlic extract (Allium sativum). International Journal of Poultry Science.17: 452-458. DOI: 10.3923/ijps.2018.452.458
Mushawwir, A., K.Y. Yong, L. Adriani, E. Hernawan and K.A. Kamil. 2010. The Fluctuation Effect of Atmospheric Ammonia (NH3) Exposure and Microclimate on Hereford Bulls Hematochemical. Journal of The Indonesian Tropical Animal Agriculture 35: 232-238. DOI: https://DOI.org/10.14710/jitaa.35.4.232-238
Mushawwir, A., N. Suwarno dan R. Permana. 2020a. Profil Total Lemak dan Protein Hati Puyuh Fase Grower dan Layer. Jurnal Ilmu dan Industri Peternakan. 6(2):65-76. DOI: http://dx.doi.org/10.24252/jiip.v6i2.18312
Mushawwir, A., A.A. Yulianti dan N. Suwarno. 2020b. Histologi Liver Burung Puyuh dengan Pemberian Minyak Atsiri Bawang Putih. Jurnal Ilmu dan Teknologi Peternakan. 8(1):1-7. DOI: http://dx.doi.org/10.24252/jitp.v8i1.32758
Mushawwir, A., N. Suwarno dan D. Latipudin. 2020c. Profil metabolik jalur glikogenolisis puyuh dalam kondisi stres panas dengan pemberian diallyl n-sulfida¬ (dn-s) organic. Jurnal Galung Tropika. 9:48-59. DOI: http://dx.doi.org/10.31850/jgt.v9i1.519
Mushawwir, A., N. Suwarno dan R. Permana. 2020d. Profil non-esterified fatty acids (NEFA) dan trigliserida ayam sentul pada sistem pemeliharaan berbeda. Jurnal Ilmu dan Industri Peternakan. 6:14-24. DOI: 10.24252/jiip.v6i1.14445
Mushawwir, A., J. Arifin, D. Darwis, T. Puspitasari, D.S. Pengerteni, N. Nuryanthi and R. Permana. 2020e. Liver metabolic activities of Pasundan cattle induced by irradiated chitosan. Biodiversitas. 21: 5571-5578. https://DOI.org/10.13057/biodiv/d211202
Mushawwir, A., R. Permana, D. Latipudin and N. Suwarno. 2021a. Organic Diallyl-n-Sulfide (Dn-S) inhibited the glycogenolysis pathway and heart failure of heat-stressed laying hens. IOP Conf. Series: Earth and Environmental Science. 788: 1-7. DOI: 10.1088/1755-1315/788/1/012091
Mushawwir, A., N. Suwarno dan R. Permana. 2021b. Dialil n-Sulfida Organik Menurunkan Kadar Lipid Plasma Darah dan Hati Itik Cihateup Fase Grower. Jurnal Ilmu dan Teknologi Peternakan Tropis. 8(1):19-25. DOI: 10.33772/jitro.v8i1.15128
Mushawwir, A., R. Permana, D. Darwin, T. Puspitasari, D. S. Pangerteni, N. Nuryanthi and N. Suwarno. 2021c. Enhancement of the liver histologic of broiler induced by irradiated chitosan (IC). IAP Conference Proceedings 2381: 0200461-0200467. DOI: https://DOI.org/10.1063/5.0066271
Na, Y.K., H.M. Sang, J.K. Seong, K.K. Eun, O. Mirae, T. Yujiao and Y. J. Se. 2020. Summer season temperature-humidity index threshold for infrared thermography in Hanwoo (Bos taurus coreanae) heifers. Asian-Australasian Journal of Animal Sciences. 33: 1691-1698.
Nurmalia, V.R., D. Rusmana dan A. Mushawwir. 2020. Kadar Glukosa Dan Trigliserida Ayam Ras Petelur Fase Layer Yang Diberi Ransum Mengandung Ekstrak Pegagan (Centella asiatica). Jurnl Ilmu Nutrisi Ternak Tropis dan Ilmu Pakan. 2(4):217-224. DOI: 10.24198/jnttip.v2i4.27396.
Pickler, L., C. Breno, B. Beirão, M. Ricardo, J. Hayashi, F. Durau, M.C. Lourenço, L .F. Caron and E. Santin. 2013. Effect of sanguinarine in drinking water on Salmonella control and the expression of immune cells in peripheral blood and intestinal mucosa of broilers J. appl. Poultry Research. 22: 430-438. https://DOI.org/10.3382/japr.2012-00649
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